185527-11-1

Basic information

• Product Name: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE
• Synonyms: TERT-BUTYL 3-AMINO-2,3-DIHYDROSPIRO[INDENE-1,4'-PIPERIDINE]-1'-CARBOXYLATE;3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE;TERT-BUTYL 3-AMINO-2,3-DIHYDRO-1'H-SPIRO[INDENE-1,4'-PIPERIDINE]-1'-CARBOXYLATE;Spiro[1H-indene-1,4'-piperidine]-1'-carboxylic acid,3-aMine- 2,3-dihydro- 1,1-diMethyl ethyl ester;Tert-Butyl 3-Amino-2,3-Dihydrospiro[Indene-1,4-Piperidine]-1-Carboxylate(WX105027)
• CAS NO: 185527-11-1
• Molecular Formula: C₁₈H₂₆N₂O₂
• Molecular Weight: 302.41124
• Mol File: 185527-11-1.mol

Chemical Properties

• Boiling Point: 431.3 °C at 760 mmHg
• Flash Point: 214.6 °C
• Appearance: /
• Density: 1.14
• Storage Temp.: 2-8°C
• PKA: 9.10±0.20(Predicted)
• CAS DataBase Reference: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE(185527-11-1)
• EPA Substance Registry System: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE(185527-11-1)

Safety Data

• Hazardous Substances Data: 185527-11-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE is used as a building block for the synthesis of various pharmaceutical drugs and biologically active molecules. Its unique spirocyclic structure and the presence of an amino group make it a valuable intermediate in the development of new drug candidates with potential therapeutic applications.
Used in Organic Synthesis:
3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE is used as a versatile intermediate in organic synthesis due to its spirocyclic structure and the presence of a BOC protective group on the nitrogen atom. This allows for selective functionalization of the piperidine nitrogen atom, enabling the synthesis of a wide range of complex organic molecules with specific properties and functions.
Used in Drug Discovery and Development:
3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE is employed as a key component in drug discovery and development processes. Its unique structural features and the ability to selectively modify the nitrogen atom make it a promising candidate for the design and synthesis of novel drug molecules with improved pharmacological properties and therapeutic potential.

Downstream Products

• 937253-91-3 tert-butyl 3-(benzoylamino)-2,3-dihydro-1'H-spiro[indene-1,4'-piperidine]-1'-carboxylate 

Relevant articles and documents

AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE

A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R 5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.

Spiro piperidines and homologs promote release of growth hormone

There are disclosed certain novel compounds identified as spiro piperidines and homologs which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, such as short stature in growth hormone deficient children, and to treat medical conditions which are improved by the anabolic effects of growth hormone. Growth hormone releasing compositions containing such spiro compounds as the active ingredient thereof are also disclosed.