185539-41-7

Upstream product

• 185539-34-8 N-[1-butyl-4-(3-methoxyphenyl)-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N'-(2,6-diisopropylphenyl)urea 

Downstream Products

• 185539-50-8 N-[1-butyl-4-{3-(3-chloropropoxy)phenyl}-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N'-(2,6-diisopropylphenyl)urea 

Relevant academic research and scientific papers

Naphthyridine derivatives

Naphthyridine derivative of the formula: STR1 wherein Ring A is substituted or unsubstituted pyridine, X is --N(R2)--CO--(R2 is H, alkyl, substituted alkyl, etc.), Z is a direct bond, --NH--, C1 -C2 alkylene, or --CH=CH--, Y is alkyl, substituted alkyl, aromatic group or substituted aromatic group, etc., B is alkyl, substituted alkyl, aromatic group or substituted aromatic group, or an acid addition salt thereof, these compounds having acyl-CoA: cholesterol acyl transferase inhibitory activity, and being useful as an agent for prophylaxis or treatment of hyperlipidemia, atherosclerosis, and related diseases thereof.