185543-40-2Relevant academic research and scientific papers
Observations on the alkylation of β-acetalic carbanions: Monoalkylation versus dialkylation and elimination
Ballini, Roberto,Bosica, Giovanna,Cossu, Sergio,De Lucchi, Ottorino,Peluso, Paola
, p. 4461 - 4465 (2007/10/03)
The reaction with methyl iodide and a base (t-BuOK) of 1,3-dioxolanes and 1,3-dithiolanes substituted at the β-position with an electron-withdrawing substituent (EWG=-CO2Me, -SO2Ph, -SO2Ph-p-NO2, -SO2Ph-o-NO2) leads to mono- or dialkylated or ring-opened products in good yield.
A Michael route to acetals and thioacetals: Preparation of acetals (thioacetals) of 2-sulfonylacetaldehyde from alkynyl and other unsaturated aryl sulfones
Cossu, Sergio,De Lucchi, Ottorino,Fabris, Fabrizio,Ballini, Roberto,Bosica, Giovanna
, p. 1481 - 1484 (2007/10/03)
A simple protocol for the direct transformation of arylsulfonylalkynes 1, (Z)- and (E)-1,2-bis(phenylsulfonyl)ethylene (2), and (E)-1-chloro-2-phenylsulfonylethylene (3) into the acetals or thioacetals of acetyl sulfones is presented. It engages the NaH-c
