185556-56-3Relevant articles and documents
New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: Synthesis, biological evaluation, and mechanism of action studies
Rodriguez, Jorge,Aran, Vicente J.,Boiani, Lucia,Olea-Azar, Claudio,Lavaggi, Maria Laura,Gonzalez, Mercedes,Cerecetto, Hugo,Maya, Juan Diego,Carrasco-Pozo, Catalina,Cosoy, Hernan Speisky
scheme or table, p. 8186 - 8196 (2010/03/25)
New 5-nitroindazole derivatives were developed and their antichagasic properties studied. Eight compounds (14-18, 20, 26 and 28) displayed remarkable in vitro activities against Trypanosoma cruzi (T. cruzi). Its unspecific cytotoxicity against macrophages