185564-87-8

Upstream product

• 611-71-2 MANDELIC ACID 
• 108-38-3 m-xylene 

Downstream Products

• 1421928-21-3 C₃₀H₃₀N₂O₂ 
• 1421838-19-8 2-(2,4-dimethylphenyl)-N-(4-hydroxybenzyl)-2-phenylacetamide 
• 1421837-27-5 C₃₀H₃₂N₂O₃ 
• 1421838-20-1 N-(4-((3,5-dimethylisoxazol-4-yl)methoxy)benzyl)-2-(2,4-dimethylphenyl)-2-phenylacetamide 
• 185564-85-6 Phenylxylylketene 
• 185564-88-9 Phenylxylylacetyl chloride 

Relevant academic research and scientific papers

Concave reagents, 21: Selective acylations of primary and secondary alcohols by ketenes

Concave pyridines 1 were used to catalyze the addition of primary and secondary alcohols to ketenes 4, and the kinetic data of these catalyses were determined. In inter- and intramolecular competitions the use of 1e-g led to improved selectivities for the acylation of primary alcohols in comparison with secondary alcohols. All primary alcohols react at comparable rates. Observed rate constants were correlated with Taft's Es values. The starting materials and products were fully characterized. VCH Verlagsgesellschaft mbH, 1996.

COMPOUNDS AND METHODS

The present invention relates to novel retinoid-related orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.

COMPOUNDS AND METHODS

The present invention relates to novel retinoid-reiated orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.