185671-07-2Relevant academic research and scientific papers
Synthesis and activity of pseudotripeptide inhibitors of HIV-1 protease containing D(-)-O-(benzyl)-tartaric acid
Marastoni, Mauro,Fantin, Giancarlo,Bortolotti, Fabrizio,Tomatis, Roberto
, p. 1099 - 1101 (2007/10/03)
Four HIV-1 protease inhibitors containing [(S,S)-O-(benzyl) tartaric acid]-Pro as a transition-state mimic were prepared and evaluated by a spectrophotometric assay. Two pseudotripeptide derivatives showed weak inhibitory activity similar to acetylpepstatin.
