185799-89-7Relevant academic research and scientific papers
Enzymatic synthesis and antiviral activity of 2'-deoxy-2'-fluoro-ribavirin
Slater, Martin J.,Gowrie, Clare,Freeman,Short
, p. 2787 - 2790 (2007/10/03)
2'-Deoxy-2'-fluoro-ribavirin has been efficiently synthesised from 2'-deoxy-2'-fluorouridine using nucleoside transferase as the key step, and evaluated for its antiviral properties in cell culture. An efficient synthesis of 3,5-di-O-p-chlorobenzoyl-2-deoxy-2-fluoro-β-D-ribofuranose is also described.
