185835-97-6

Basic information

• Product Name: (5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE
• Synonyms: (5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE;SL251188
• CAS NO: 185835-97-6
• Molecular Formula: C16H17 F3 N2 O5
• Molecular Weight: 374.31
• Mol File: 185835-97-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 444.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.358±0.06 g/cm3(Predicted)
• PKA: -1.10±0.30(Predicted)
• CAS DataBase Reference: (5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE(185835-97-6)
• EPA Substance Registry System: (5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE(185835-97-6)

Safety Data

• Hazardous Substances Data: 185835-97-6(Hazardous Substances Data)

Usage

General Description

The chemical compound "(5S)-5-(methoxymethyl)-3-[6-(4,4,4-trifluorobutoxy)-1,2-benzoxazol-3-yl]-1,3-oxazolidin-2-one" is a complex heterocyclic compound. It is a derivative of oxazolidinone and contains a benzoxazolyl moiety. The presence of a methoxymethyl group and a trifluorobutoxy group in the molecule contribute to its unique chemical properties. (5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE may have potential applications in pharmaceuticals, agrochemicals, and materials science due to its diverse structural features and potential biological activities. Further research is needed to explore its potential uses and properties in various fields.

Upstream product

• 185836-35-5 2-fluoro-4-phenylmethoxybenzonitrile 
• 185836-40-2 ethyl 6-(benzyloxy)benzo[d]isoxazol-3-ylcarbamate 
• 406-81-5 1-Bromo-4,4,4-trifluorobutane 

Relevant articles and documents

“In-loop” [11C]CO2 fixation: Prototype and proof of concept

Carbon-11-labeled carbon dioxide is the most common feedstock for the synthesis of positron emission tomography radiotracers and can be directly used for 11C-carbonylation. Herein, we report the development of an apparatus that takes advantage of “in-loop” technologies to facilitate robust and reproducible syntheses of 11C-carbonyl-based radiotracers by [11C]CO2-fixation. Our “in-loop” [11C]CO2-fixation method is simple, efficient, and proceeds smoothly at ambient pressure and temperature. We selected model 11C-carbonyl-labeled carbamates as well as symmetrical and unsymmetrical ureas based on their widespread use in radiotracer design and our clinical research interests for proof of concept. Utility of this method is demonstrated by the synthesis of a reversible radiopharmaceutical for monoamine oxidase B, [11C]SL25.1188, and 2 novel fatty acid amide hydrolase inhibitors. These radiotracers were isolated and formulated (>3.5?GBq; 100?mCi) with radiochemical purities (>99%) and molar radioactivity (≥80?GBq/μmol; ≥2162?mCi/μmol).