185836-77-5

Upstream product

• 497-19-8 sodium carbonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 185836-76-4 tert-butyl (R)-4-hydroxy-3-methylbutanoate 
• 185836-75-3 (R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid 

Downstream Products

• 185836-73-1 (3R)-3-Methyl-4-[4-[4-(4-pyridyl)piperazin-1-yl]phenoxy]-butyric acid hydrochloride 
• 63314-79-4 (3S,5E)-3-methylcyclopentadec-5-enone 
• 63314-79-4 (3S,5Z)-3-methylcyclopentadec-5-enone 
• 63314-79-4 (-)-(R,E)-3-methyl-5-cyclopentadecen-1-one 
• 63314-79-4 (3R,5Z)-3-methylcyclopentadec-5-enone 
• 391208-04-1 (R)-2-methylpent-4-en-1-yl 4-methylbenzenesulfonate 
• 132857-79-5 (S)-2-methylpent-4-en-1-yl 4-methylbenzenesulfonate 

Relevant academic research and scientific papers

Synthesis of (R)- and (S)- muscone

(R)-(-)-Muscone (3-methylcyclopentadecanone, 1) the key perfumery component isolated from the male musk deer, Moschus moschiferus,* was synthesized from the easily available chiral building block, (R)-3-tert-butoxycarbonyl-2- methylpropanoic acid (2), by employing ring-closing olefin metathesis (RCM). Antipode (+)-1 was also synthesized in a similar manner from tert-butyl (S)-3-methoxycarbonylbutanoate (10). *(a) Walbaum, H. J. J. Prakt. Chem., 73, 488 (1906); (b) Ruzicka, L., Further considerations on the constitution of muscone. Helv. Chim. Acta, 9, 715, 1008-1017 (1926).

Heterocyclic compouds

A compound of the general formula wherein: n is 0 or 1; M1 is an amino group; Q is an aromatic heterocyclic group containing a basic nitrogen atom; M2 is an imino group; L is a template group; and A is an acidic group, or an ester or amide derivative thereof, or a sulphonamide group; and pharmaceutically acceptable salts and pro-drugs thereof, for use in the treatment of a disease in which platelet aggregation mediated by the binding of adhesion molecules to GPIIb-IIIa is involved. Novel compounds are also disclosed.