185903-69-9

Upstream product

• 185903-63-3 (R)-4-Benzyl-3-((2R,3S)-3-hydroxy-2,6-dimethyl-hept-6-enoyl)-oxazolidin-2-one 
• 185903-65-5 (2S,3S)-2,6-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-hept-6-enal oxime 
• 185903-68-8 (2R,5S,6R)-2-Hydroxymethyl-2,6-dimethyl-5-(tetrahydro-pyran-2-yloxy)-cyclohexanone 
• 185903-64-4 (2S,3S)-2,6-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-hept-6-en-1-ol 
• 3973-43-1 4-methylpent-4-enal 
• 123522-72-5 Tributyl-[(E)-2-(2,2-dimethyl-[1,3]dioxan-5-yl)-vinyl]-stannane 
• 185903-71-3 (2R,5S,6R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-2,6-dimethyl-5-(tetrahydro-pyran-2-yloxy)-cyclohexanone 

Downstream Products

• 117479-71-7 (+)-Cassiol 
• 185903-70-2 (2S,3S,4R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-3-[(E)-2-(2,2-dimethyl-[1,3]dioxan-5-yl)-vinyl]-3-hydroxy-2,4-dimethyl-cyclohexanone 

Relevant academic research and scientific papers

An enantioselective total synthesis of (+)-cassiol

An enantioselective total synthesis of (+)-cassiol 1 possessing potent antiulcerogenic activity has been accomplished by using an efficient construction methodology of the asymmetric quaternary carbon center via a highly diastereoselective intramolecular [3+2] dipolar cycloaddition reaction of the nitrile oxide 10 as a key step.