185944-56-3Relevant academic research and scientific papers
2-Aminoalcohol immunosuppressants: Structure-activity relationships
Hirose, Ryoji,Hamamichi, Norimitsu,Kitao, Yuuki,Matsuzaki, Tohru,Chiba, Kenji,Fujita, Tetsuro
, p. 2647 - 2650 (2007/10/03)
The 2-aminoalcohol series of immunosuppressants showed a bell-shaped relationship between the activity and the carbon number. The (R)-isomers were more potent than the (S)-isomers, and (R)-2-aminohexadecanol displayed comparably activity to a potent immunosuppressant, FTY720.
