185961-99-3

Basic information

• Product Name: 1-(piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one
• Synonyms: 1-(piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one;2H-IMidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1-(4-piperidinyl)-;1-Piperidin-4-yl-1,3-dihydro-iMidazo[4,5-b]pyridin-2-one;1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one;1,3-dihydro-1-(4-piperidinyl)-2h-imidazo[4,5-b]pyridin-2-one;185961-99-3
• CAS NO: 185961-99-3
• Molecular Formula: C₁₁H₁₄N₄O
• Molecular Weight: 218.25506
• Mol File: 185961-99-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.272g/cm³
• Refractive Index: 1.601
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-(piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one(185961-99-3)
• EPA Substance Registry System: 1-(piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one(185961-99-3)

Safety Data

• Hazardous Substances Data: 185961-99-3(Hazardous Substances Data)

Usage

General Description

1-(piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one is a scientific name of a chemical compound. It is comprised of a complex fusion of several organic compounds including piperidine, a heterocyclic compound, and imidazo, which belongs to a class of diazoles. The structure also includes the element of pyridinone, a derivative of pyridine, an aromatic compound. The specific properties, toxicity, and uses of this precise chemical highly depend on its molecular structure and functional groups, as well as the specific context in which it is synthesized and deployed. It has potential uses in pharmacology and biochemistry based on its complex structure but detailed scientific research is necessary to fully comprehend and harness its potential.

InChI:InChI=1/C11H14N4O/c16-11-14-10-9(2-1-5-13-10)15(11)8-3-6-12-7-4-8/h1-2,5,8,12H,3-4,6-7H2,(H,13,14,16)

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Downstream Products

• 1168106-91-9 1-(1-([4-chloro-5-(2,3-dichlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetyl)-4-piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1168104-62-8 1-(1-([5-(2-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetyl)-4-piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1168104-64-0 1-(1-([5-(2-chlorophenyl)-4-(1-pyrrolidinyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetyl)-4-piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1168106-99-7 1-(1-([5-(2-chlorophenyl)-4-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetyl)-4-piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1168104-68-4 1,1-dimethylethyl 4-(5-(2-chlorophenyl)-7-(2-oxo-2-[4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinyl]ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1-piperazinecarboxylate 
• 1168104-86-6 1-(1-([5-(2-chlorophenyl)-4-ethyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetyl)-4-piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1095273-42-9 1-[1-({5-[3-chloro-5-(methyloxy)phenyl]-1,3,4-oxadiazol-2-yl}acetyl)-4-piperidinyl]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1095273-39-4 1-(1-{[5-(5-chloro-3-biphenylyl)-1,3,4-oxadiazol-2-yl]acetyl}-4-piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1095273-52-1 1-[1-({5-[3-methyl-5-(4-morpholinyl)phenyl]-1,3,4-oxadiazol-2-yl}acetyl)-4-piperidinyl]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1219921-64-8 C₃₁H₃₁N₇O₄ 
• 1219921-59-1 C₂₁H₁₉ClN₆O₃ 
• 1219921-61-5 C₂₁H₁₈Cl₂N₆O₃ 
• 1095273-50-9 1-(1-{[5-(2,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl}-4-piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1219921-62-6 C₂₁H₁₈Cl₂N₆O₃ 

Relevant articles and documents

Novel Compounds

The present invention relates to the new compounds of general formula I wherein A, U, V, X, Y, R1, R2 and R3 are defined as stated hereinafter, the tautomers, the isomers thereof, the diastereomers, the enantiomers, the hydrates, the mixtures and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, their use and processes for preparing them.

NOVEL COMPOUNDS

The present invention relates to new CGRP-antagonists of general formula I wherein U, V, X, Y, R1, R2, R3 and R4 are defined as mentioned in the description, the tautomers thereof, the isomers thereof, the diastereomers thereof, the enantiomers thereof, the hydrates thereof, the mixtures thereof and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, the use thereof and processes for the preparation thereof.