185980-43-2Relevant academic research and scientific papers
Method for the synthesis of bis-tetrahydrofuranyl Annonaceous acetogenins
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, (2008/06/13)
A method for the synthesis of bis-tetrahydrofuranyl Annonaceous acetogenins, including the natural products and analogs thereof, is provided which proceeds by the Pd-mediated coupling of a bis-tetrahydrofuranyl-subunit comprising a terminal alkyne, with a (C4)-hydroxybutenolide subunit comprising a terminal vinyl iodide, followed by selective reduction of the resulting enyne.
