185995-63-5Relevant academic research and scientific papers
Synthesis of antineoplastic analogs of aplysiatoxin with various side chain structures
Shu, Yuki,Yanagita, Ryo C.,Tokuda, Harukuni,Suzuki, Nobutaka,Irie, Kazuhiro
, p. 281 - 303 (2012)
We have recently developed a simplified analog of aplysiatoxin with anti-proliferative activity (1). To investigate the structure-activity relationship of its side chain, an alternative synthetic route of 1 has been established. Via the key intermediate 6
