FMoc-PNA-G(Bhoc)-OH is a synthetic chemical compound that is a modified form of peptide nucleic acid (PNA), which is an artificial nucleic acid analog. FMoc-PNA-G(Bhoc)-OH is utilized in biochemistry and molecular biology research. It features a fluorenylmethoxycarbonyl (FMoc) protecting group, a guanine (G) base, and a 1,3-bis(hydroxymethyl)benzene (Bhoc) group. These components contribute to the stabilization of the PNA structure and enhance its binding affinity to complementary DNA or RNA sequences, making it a valuable tool in the development of PNA-based diagnostic tools and therapeutic agents for targeted gene modulation and molecular recognition.
186046-83-3
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Basic information
- Product Name: FMoc-PNA-G(Bhoc)-OH
- Synonyms: FMoc-PNA-G(Bhoc)-OH
- CAS NO:186046-83-3
- Molecular Formula: C40H35N7O8
- Molecular Weight: 741.748
- EINECS: N/A
- Product Categories: N/A
- Mol File: 186046-83-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: 1.43±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 3.31±0.10(Predicted)
- CAS DataBase Reference: FMoc-PNA-G(Bhoc)-OH(CAS DataBase Reference)
- NIST Chemistry Reference: FMoc-PNA-G(Bhoc)-OH(186046-83-3)
- EPA Substance Registry System: FMoc-PNA-G(Bhoc)-OH(186046-83-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 186046-83-3(Hazardous Substances Data)
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186046-83-3 Usage
Uses
Used in Biochemistry and Molecular Biology Research:FMoc-PNA-G(Bhoc)-OH is used as a research tool for the development of PNA-based diagnostic tools and therapeutic agents. Its unique structure allows for high specificity and affinity to DNA or RNA sequences, which is crucial for targeted gene modulation and molecular recognition applications.
Used in Gene Therapy:
In the field of gene therapy, FMoc-PNA-G(Bhoc)-OH is used as a component in the design of PNA molecules that can specifically target and modulate genes. This allows for the regulation of gene expression and has potential applications in treating genetic disorders and diseases.
Used in Antisense Technologies:
FMoc-PNA-G(Bhoc)-OH is utilized in antisense technologies as a building block for the creation of PNA molecules that can hybridize to specific RNA sequences, thereby inhibiting their function. This can be applied to silence disease-causing genes or to control gene expression in research settings.
Used in Diagnostic Tool Development:
In the development of diagnostic tools, FMoc-PNA-G(Bhoc)-OH is used to create PNA probes that can specifically recognize and bind to target DNA or RNA sequences. This allows for the detection and quantification of specific genetic markers, which can be useful in disease diagnosis and monitoring.
Used in Drug Development:
FMoc-PNA-G(Bhoc)-OH is used in the pharmaceutical industry for the development of PNA-based drugs that can modulate gene expression or interfere with the function of specific RNA molecules. This can lead to the creation of new therapeutic agents for various diseases, including cancer and genetic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 186046-83-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,0,4 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.Calculate Digit Verification of CAS Registry Number 186046-83:
(8*1)+(7*8)+(6*6)+(5*0)+(4*4)+(3*6)+(2*8)+(1*3)=153
153 % 10 = 3
So 186046-83-3 is a valid CAS Registry Number.
186046-83-3Upstream product
186046-83-3Downstream Products
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FMoc-PNA-G(Bhoc)-OH
