186087-71-8

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 184637-30-7 C₃₀H₄₆O₅Si 

Downstream Products

• 186087-61-6 C₃₄H₅₄O₅Si 
• 186087-63-8 (Z)-(2R,4R,6S,9R,13S,15S)-2,10-Dimethoxy-6-(4-methoxy-benzyloxy)-5,5,9-trimethyl-tricyclo[11.2.1.0^4,9]hexadeca-1⁽¹⁶⁾,10-dien-15-ol 
• 186087-65-0 [(Z)-(2R,4R,6S,9R,13R)-2,10-Dimethoxy-6-(4-methoxy-benzyloxy)-5,5,9-trimethyl-tricyclo[11.2.1.0^4,9]hexadeca-1⁽¹⁶⁾,10,14-trien-15-yloxy]-trimethyl-silane 
• 186087-66-1 (Z)-(2R,4R,6S,9R,13R)-14-Dimethylaminomethyl-2,10-dimethoxy-6-(4-methoxy-benzyloxy)-5,5,9-trimethyl-tricyclo[11.2.1.0^4,9]hexadeca-1⁽¹⁶⁾,10-dien-15-one 
• 186087-67-2 (Z)-(2R,4R,6S,9R,13R)-2,10-Dimethoxy-6-(4-methoxy-benzyloxy)-5,5,9-trimethyl-14-methylene-tricyclo[11.2.1.0^4,9]hexadeca-1⁽¹⁶⁾,10-dien-15-one 
• 186087-64-9 (Z)-(2R,4R,6S,9R,13S)-2,10-Dimethoxy-6-(4-methoxy-benzyloxy)-5,5,9-trimethyl-tricyclo[11.2.1.0^4,9]hexadeca-1⁽¹⁶⁾,10-dien-15-one 
• 196939-48-7 (2R,4R,6S,9R,13S,15S)-2-Methoxy-6-(4-methoxy-benzyloxy)-5,5,9-trimethyl-15-(2-trimethylsilanyl-ethoxy)-tricyclo[11.2.1.0^4,9]hexadec-1⁽¹⁶⁾-en-10-one 
• 196939-46-5 (1R,1'R,3'R,4'aR,5S,6'S,8'aR)-3',4',4'a,5',6',7',8',8'a-octahydro-3'-methoxy-6'-[(p-methoxybenzyl)oxy]-5',5',8'a-trimethyl-5-[2-(trimethylsilyl)ethoxy]-1'-vinylspiro(2-cyclopentene-1,2'(1'H)-naphthalene)-1'ol 
• 196939-47-6 (2R,4R,6S,9R,13S,15S)-2-Hydroxy-6-(4-methoxy-benzyloxy)-5,5,9-trimethyl-15-(2-trimethylsilanyl-ethoxy)-tricyclo[11.2.1.0^4,9]hexadec-1⁽¹⁶⁾-en-10-one 
• 186087-73-0 (1R,1'R,3'R,4'aR,6'S,8'aR)-3',4',4'a,5',6',7',8',8'a-octahydro-6'-[(p-methoxybenzyl)oxy]-5',5',8'a-trimethyl-5-[2-(trimethylsilyl)ethoxy]-1'-vinylspiro(2-cyclopentene-1,2'(1'H)-naphthalene)-1',3'-diol 
• 186087-72-9 C₃₂H₄₈O₅Si 

Relevant academic research and scientific papers

Synthetic entry into the ent-kaurene framework. Application of an unprecedented transannular cyclization for forming the central bond common to the B and C rings

A stereocontrolled means for constructing the ent-kaurene framework is described. The key transformation involves transannular ring closure of an 8,9-seco precursor with migration of an interstitial methoxyl group.

First synthesis of cytotoxic 8,9-secokaurene diterpenoids. An enantioselective route to (-)-O-methylshikoccin and (+)- O-methylepoxyshikoccin

A practical route for the total synthesis of 8,9-secokaurene diterpenes is described. The central step is the 3.3]sigmatropic rearrangement of spirocyclic intermediates such as 35, 40, and 41. All three compounds must necessarily respond identically to pr