18610-64-5Relevant articles and documents
Characterization of the degradation products of luteinizing hormone releasing hormone
Motto,Hamburg,Graden,Shaw,Cotter
, p. 419 - 423 (1991)
The degradation products of luteinizing hormone releasing hormone [LH/RH; 1; gonadorelin releasing hormone (GnRH); 2] were determined in aqueous solution (pH 6.5) at 25, 37, 50, and 80 °C. The predominant route of degradation involved the cleavage of the 2 to the free acid form in peptides 4 and 10. Racemization of the serine and histidine residues to give peptides 2 and 3 was a second route of degradation.