186134-88-3Relevant academic research and scientific papers
Thermal addition reaction of aroylketene with ethyl vinyl ether: Aromatic substituent effect on aroylketene reactivity
Toda, Jun,Saitoh, Toshiaki,Oyama, Taichi,Horiguchi, Yoshie,Sano, Takehiro
, p. 2457 - 2464 (2007/10/03)
A series of aroylketenes (2) generated by thermolysis of 5-aryl-2,3-dihydrofuran-2,3-diones (1) reacted with ethyl vinyl ether under a thermal condition to give 2,3-dihydro-4H-pyran-4-ones (3) and/or 4H-pyran-4-ones (4). In this reaction the electron withdrawing substituent (NO2, Cl) introduced into the aryl part enhanced the ketene reactivity (2b-e), while the electron donating one (OMe) did not affect its reactivity (2f-g) in a significant extent. The heteroaroylketenes (2h) and (2i) showed a fairly good reactivity.
