186140-19-2Relevant academic research and scientific papers
Synthetic applications of bis(iminophosphoranes) - Preparation of some derivatives of the 11H-quinazolino[2,3-b]- and quinazolino[4,3-b]quinazoline ring systems
Molina, Pedro,Conesa, Carlota,De Los Desamparados Velasco
, p. 107 - 110 (2007/10/03)
Aza Wittig reaction of bis(iminophosphorane) 3 with two equivalents of aryl isocyanates directly provided the bicyclic guanidines 4. However, 3 undergoes intramolecular aza Wittig reaction on thermal treatment to give the iminophosphorane 6 derived from the 2-(o-azidophenyl)-4(3H)-quinazolinone. Compound 6 reacts with isocyanates, acyl chlorides and carbon disulfide to yield quinazolino[4,3-b]quinazoline derivatives 8a-c, 9a-c, 10, and 11. VCH Verlagsgesellschaft mbH, 1997.
