18615-08-2Relevant academic research and scientific papers
A convenient method for [14C]Carbonylation reactions
Elmore, Charles S.,Dean, Dennis C.,Melillo, David G.
, p. 1135 - 1144 (2007/10/03)
A simple, efficient method for generation of 14CO from Ba14CO3 has been developed. Reduction of 14CO2 using LiBEt3H gave [14C]formate in good yield which was treated with conc. H2SO4 to effect dehydration to 14CO. Through direct attachment of a reaction vessel containing aryl substrate and Pd(0) catalyst, [14C]carbonylation reactions were performed without the use of a mercury transfer pump. [14C]Carbonylation reactions using 14CO generated in this manner have been shown to proceed in good yield with a variety of substrates.
Syntheses of N-t-butyl-α-phenylnitrone-α-14C and α-(4-pyridyl-1-oxide)-N-t-butylnitrone-α-14C
Le, Diem Duy,Zhang, Yinsheng,Chien, David H.,Moravek, Josef
, p. 1119 - 1125 (2007/10/03)
N-t-Butyl-α-phenylnitrone-α-14C was prepared from benzoic-α-14C acid via benzyl alcohol in 40 - 55% yield (sp. activity: 30 mCi/mmol). α-(4-Pyridyl-1-oxide)-N-t-butylnitrone-α-14C arrived from Ba14CO3
Synthesis of optically pure (D-phenyl[3-14C]alanine
Koltai,Alexin,Rutkai,Toth-Sarudy
, p. 977 - 982 (2007/10/03)
Lithium aluminium hydride reduction of methyl [7-14C]benzoate gave [7-14C]benzyl alcohol which was transformed (HBr, H2SO4) to [7-14C]benzyl bromide. The latter was reacted with lithium N-(bis-methylt
