18622-70-3Relevant academic research and scientific papers
Iodine(III)-mediated aromatic amidation vs olefin amidohydroxylation. The amide N-substituent makes the difference
Serna, Sonia,Tellitu, Imanol,Domínguez, Esther,Moreno, Isabel,Sanmartin, Raúl
, p. 6533 - 6539 (2007/10/03)
A series of N-methoxy- and N-para-methoxyphenylacetamides simultaneously substituted at the α position by a benzyl and an allyl group have been treated with phenyliodine(III)bis(trifluoroacetate) to generate stabilized N-acylnitrenium intermediates. It ha
A STEREOSELECTIVE SYNTHESIS OF 5-ARYL- AND 6-ARYLOXAZOLOISOQUINOLINES
Kano, Shinzo,Yuasa, Yoko,Shibuya, Shiroshi
, p. 2327 - 2333 (2007/10/02)
Reduction of N-(α,β-diaryl)ethyl and N-(β,β-diaryl)ethyl ethoxycarbonylmethyl carbamates, obtained from the corresponding 2,3-diaryl- and 3,3-diarylpropionic acids, with diisobutylaluminum hydride, followed by cyclization with formic acid at room temperature gave the corresponding 5-aryl and 6-aryl-oxazoloisoquinolines, respectively, with high stereoselectivity.
