18625-03-1

Basic information

• Product Name: 3-SULFAMOYL-L-ALANINE
• Synonyms: 3-SULFAMOYL-L-ALANINE;L-(+)-2-amino-3-sulfamoylpropionic acid
• CAS NO: 18625-03-1
• Molecular Formula: C3H8 N2 O4 S
• Molecular Weight: 0
• Mol File: 18625-03-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 433°Cat760mmHg
• Flash Point: 215.7°C
• Appearance: /
• Density: 1.657g/cm³
• Vapor Pressure: 1.04E-08mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 3-SULFAMOYL-L-ALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-SULFAMOYL-L-ALANINE(18625-03-1)
• EPA Substance Registry System: 3-SULFAMOYL-L-ALANINE(18625-03-1)

Safety Data

• Hazardous Substances Data: 18625-03-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H8N2O4S/c4-2(3(6)7)1-10(5,8)9/h2H,1,4H2,(H,6,7)(H2,5,8,9)

Upstream product

• 33662-44-1 (R)-2-benzyloxycarbonylamino-3-sulfamoylpropanoic acid ethyl ester 
• 33662-45-2 (2R)-2-N(benzyloxycarbonyl)amino-3-aminosulfonylpropanoic acid 
• 64957-11-5 (R)-2-benzyloxycarbonylamino-3-sulfamoyl-propionic acid benzyl ester 
• 16435-47-5 (R)-2-acetylamino-3-sulfamoyl-propionic acid methyl ester 

Relevant articles and documents

Preparation method of 3-aminosulfonyl alanine

The invention relates to the field of compound preparation, in particular to a preparation method of 3-sulfanilamide alanine shown as a formula (I). According to the method, commercially available L/D-cystine bis(tert-butyl ester) dihydrochloride is used as a raw material, the compound shown in the formula (I) can be efficiently prepared through Boc protection, oxidation reaction and deprotection,compared with a reported route, chlorine and ammonia irritant toxic gas is avoided, the synthesis route is short, the yield is high, the aftertreatment method is simple and convenient, and the methodhas very good industrial value.