18627-37-7Relevant academic research and scientific papers
A solid-phase synthetic route to N-acylated α-alkyl-D,L-homoserine lactones
Ali, Ahmed I. M.,O'Donnell, Martin J.,Samaritoni, J. Geno,Scott, William L.
, (2020)
A synthetic route to N-acylated α-alkyl-D,L-homoserine lactones was established using solid-phase unnatural peptide synthesis (UPS) and combinatorial chemistry. The application of UPS methodology allowed access to racemic N-acylated homoserine lactones (D,L-AHLs) and their α-alkyl structural analogs (α-R1-D,L-AHLs). The synthesis and characterization of a library of five D,L-AHLs and ten α-R1-D,L-AHLs prepared from resin-bound amino acids is reported.
