18628-73-4

Basic information

• Product Name: O,O-dibutyl methylphosphonothioate
• CAS NO: 18628-73-4
• Molecular Formula: C₉H₂₁O₂PS
• Molecular Weight: 224.3006
• Mol File: 18628-73-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 255.9°C at 760 mmHg
• Flash Point: 108.6°C
• Density: 1.011g/cm³
• Vapor Pressure: 0.0254mmHg at 25°C
• Refractive Index: 1.465
• CAS DataBase Reference: O,O-dibutyl methylphosphonothioate(CAS DataBase Reference)
• NIST Chemistry Reference: O,O-dibutyl methylphosphonothioate(18628-73-4)
• EPA Substance Registry System: O,O-dibutyl methylphosphonothioate(18628-73-4)

Safety Data

• Hazardous Substances Data: 18628-73-4(Hazardous Substances Data)

Upstream product

• 71-36-3 butan-1-ol 
• 676-98-2 methylphosphonothioic dichloride 
• 17529-47-4 thiophosphonic acid O,O'-dibutyl ester 
• 74-88-4 methyl iodide 
• 2372-45-4 sodium butanolate 
• 59360-02-0 methyl phosphonous acid O,O-dibutyl ester 

Downstream Products

• 18005-42-0 Methyl-thiophosphonsaeure-O-butylester 
• 15536-25-1 Methylphosphonsaeure-butylester-mercaptobutylester 

Relevant articles and documents

Synthesis method of synthetic intermediate methyl phosphite monoester of glufosinate ammonium

The invention belongs to the technical field of synthesis of glufosinate ammonium and in particular relates to a synthesis method of a synthetic intermediate methyl phosphite monoester of glufosinateammonium. Aiming at the common problem of an existing methyl phosphite monoester synthesis method that the cost is too high so that the existing methyl phosphite monoester synthesis method is not applicable to large-scale industrial production, the synthesis method provided by the technical scheme comprises the following steps: [1], enabling methylphosphonothioic dichloride to react with a hydroxyl compound under the action of an alkali A, so as to obtain diethyl methylphosphonothionate; [2], dissolving the diethyl methylphosphonothionate into a solvent B to prepare a diethyl methylphosphonothionate solution; carrying out hydrolysis reaction under the action of an alkali B to generate methylphosphonothioic monoester; [3], dissolving the methylphosphonothioic monoester into a solvent C to prepare a methylphosphonothioic monoester solution; carrying out desulfurization reaction on the methylphosphonothioic monoester solution under the action of a catalyst to prepare the methyl phosphitemonoester. The synthesis method provided by the invention is applicable to a glufosinate ammonium synthesis industry.

PHASE-TRANSFER CATALYTIC ALKYLATION OF HYDROTHIOPHOSPHORYL COMPOUNDS. IV. REACTIONS WITH PRIMARY ALKYL HALIDES

A convenient general method for the synthesis of compounds containing a thiophosphoryl group was elaborated on the basis of the Michaelis-Becker reaction with the use of the method of phase-transfer catalysis. The influence of the nature of the hydrothiophosphoryl compounds, of the alkylating agents, and of the reaction conditions on the yields of alkylated products was investigated in detail.