186299-34-3

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Basic information

Product Name: EUK 118
Synonyms: EUK 118;GCPWLPOEKJZABB-AIMLMLFYSA-M
CAS NO:186299-34-3
Molecular Formula: C22H25Mn3N2O8-3
Molecular Weight: 610.256647
EINECS: N/A
Product Categories: N/A
Mol File: 186299-34-3.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: EUK 118(CAS DataBase Reference)
NIST Chemistry Reference: EUK 118(186299-34-3)
EPA Substance Registry System: EUK 118(186299-34-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 186299-34-3(Hazardous Substances Data)

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186299-34-3 Usage

Uses

EUK 8 and EUK 134 are synthetic catalytic scavengers of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. EUK 118 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity. EUK 118 exhibits a catalase activity of 35 μM O2 formed/minute from 10 mM hydrogen peroxide, which is more than four times lower that that observed for EUK 8 under the same conditions. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 and EUK 8 with IC50 values of 2 and 0.7 μM, respectively. EUK 118 did not protect human dermal fibroblasts against hydrogen peroxide-induced cell death.

Check Digit Verification of cas no

The CAS Registry Mumber 186299-34-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,2,9 and 9 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 186299-34:
(8*1)+(7*8)+(6*6)+(5*2)+(4*9)+(3*9)+(2*3)+(1*4)=183
183 % 10 = 3
So 186299-34-3 is a valid CAS Registry Number.

186299-34-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	EUK 118

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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