186320-10-5 Usage
General Description
4-[(furan-2-ylmethyl)-carbamoyl]-butyric acid is a chemical compound with the molecular formula C11H13NO4. It is a derivative of butyric acid and contains a furan ring. 4-[(FURAN-2-YLMETHYL)-CARBAMOYL]-BUTYRIC ACID has potential pharmaceutical applications, particularly in the field of drug design and development. It may have biological activities and has been studied for its potential therapeutic effects in various medical conditions. Additionally, it is also used as a chemical intermediate in the synthesis of various organic compounds. Further research and experimentation are needed to fully understand the potential uses and effects of this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 186320-10-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,3,2 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 186320-10:
(8*1)+(7*8)+(6*6)+(5*3)+(4*2)+(3*0)+(2*1)+(1*0)=125
125 % 10 = 5
So 186320-10-5 is a valid CAS Registry Number.
186320-10-5Relevant articles and documents
Traceless Release of Alcohols Using Thiol-Sensitive Oxanorbornadiene Linkers
Aioub, Allison G.,Higginson, Cody J.,Finn
, p. 3233 - 3236 (2018/06/11)
A class of ester-amide oxanorbornadiene (EA-OND) molecules was developed to release alcohol cargos by succinimide formation upon addition of a thiol reagent. The resulting ring-closed adducts undergo further fragmentation by retro-Diels-Alder reaction to release a furan moiety in a manner similar to oxanorbornadiene diesters. The rates of each of these fragmentation pathways in the same medium were found to be sensitive to the steric nature of the amide substituent. Alcohol release was much faster in protic solvents than in aprotic ones, suggesting that this system may be useful for rapid response to thiols in biological environments. Accordingly, the attachment and thiol-dependent release of cholesterol was characterized as an example of the manipulation of a drug-like cargo.