FMOC-BACLOFIN, a derivative of the GABA receptor agonist baclofen, is characterized by the protection of its amino group by the FMOC molecule. FMOC-BACLOFIN is widely recognized for its role as a building block in the synthesis of peptoids, which are peptidomimetics with significant applications in drug discovery and materials science. The FMOC-BACLOFIN's ability to be efficiently deprotected under basic conditions during solid-phase synthesis contributes to its value in the development of novel therapeutic compounds and materials.
186320-20-7
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Basic information
- Product Name: FMOC-BACLOFIN
- Synonyms: 3-(4-CHLOROPHENYL)-4-N-FMOC-AMINOBUTYRIC ACID;FMOC-4-AMINO-3-(4-CHLOROPHENYL)BUTANOIC ACID;FMOC-BACLOFIN
- CAS NO:186320-20-7
- Molecular Formula: C25H22ClNO4
- Molecular Weight: 435.9
- EINECS: N/A
- Product Categories: N/A
- Mol File: 186320-20-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 659.1 °C at 760 mmHg
- Flash Point: 352.4 °C
- Appearance: /
- Density: 1.311 g/cm3
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: FMOC-BACLOFIN(CAS DataBase Reference)
- NIST Chemistry Reference: FMOC-BACLOFIN(186320-20-7)
- EPA Substance Registry System: FMOC-BACLOFIN(186320-20-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 186320-20-7(Hazardous Substances Data)
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186320-20-7 Usage
Uses
Used in Drug Discovery:FMOC-BACLOFIN is used as a key building block for the synthesis of peptoids, which are structurally similar to peptides but possess unique properties that make them attractive for drug development. FMOC-BACLOFIN's stability and versatility facilitate the creation of new therapeutic agents with potential applications in various medical fields.
Used in Materials Science:
In the field of materials science, FMOC-BACLOFIN is utilized as a component in the design and synthesis of advanced materials with specific properties. Its role in peptoid synthesis allows for the engineering of materials with tailored characteristics for use in diverse applications, such as sensors, biomaterials, and nanotechnology.
Used in Solid-Phase Synthesis:
FMOC-BACLOFIN is particularly valuable in solid-phase synthesis due to the ease with which the FMOC protecting group can be removed under basic conditions. This feature enables the efficient elongation of the peptoid chain, streamlining the process of creating complex peptoid structures for various applications.
Overall, FMOC-BACLOFIN's multifaceted utility in peptoid synthesis underscores its importance in both the pharmaceutical and materials science industries, driving innovation in the development of new compounds and materials with broad applications.
Check Digit Verification of cas no
The CAS Registry Mumber 186320-20-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,3,2 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.Calculate Digit Verification of CAS Registry Number 186320-20:
(8*1)+(7*8)+(6*6)+(5*3)+(4*2)+(3*0)+(2*2)+(1*0)=127
127 % 10 = 7
So 186320-20-7 is a valid CAS Registry Number.
186320-20-7Upstream product
186320-20-7Downstream Products
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FMOC-BACLOFIN
