186342-55-2

Basic information

• Product Name: N-(Dicyclopropylmethyl)-N-propyl-N-[4-(2,4,6-trimethoxyphenyl)pyrimidin-2-yl]amine
• Synonyms: NBI-27155
• CAS NO: 186342-55-2
• Molecular Formula: C₂₃H₃₁N₃O₃
• Molecular Weight: 397.52182
• Mol File: 186342-55-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(Dicyclopropylmethyl)-N-propyl-N-[4-(2,4,6-trimethoxyphenyl)pyrimidin-2-yl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(Dicyclopropylmethyl)-N-propyl-N-[4-(2,4,6-trimethoxyphenyl)pyrimidin-2-yl]amine(186342-55-2)
• EPA Substance Registry System: N-(Dicyclopropylmethyl)-N-propyl-N-[4-(2,4,6-trimethoxyphenyl)pyrimidin-2-yl]amine(186342-55-2)

Safety Data

• Hazardous Substances Data: 186342-55-2(Hazardous Substances Data)

Upstream product

• 832-58-6 1-(2,4,6-trimethoxyphenyl)ethanone 
• 135159-25-0 (2,4,6-trimethoxyphenyl)boronic acid 
• 107-08-4 1-iodo-propane 

Relevant articles and documents

Design, synthesis, and SAR of 2-dialkylamino-4-arylpyrimidines as potent and selective corticotropin-releasing factor1 (CRF1) receptor antagonists

A series of 2-dialkylamino-4-phenylpyrimidines (7) was designed and synthesized as CRF1 antagonists. SAR studies of this series resulted in the discovery of potent and selective antagonists 7b and 7n bearing a 4-(2,4,6-trisubstituted-phenyl) ring and a bulky 2-(N-bis(cyclopropane)methyl-N- propyl)amino group.