186353-05-9

Usage

Uses

Used in Organic Synthesis:
[N-methyl-N-phenyl]carbamic acid chloromethyl ester is utilized as a reagent in organic synthesis, specifically for the formation of amide bonds. Its unique structure allows it to facilitate crucial chemical reactions, making it a valuable component in this field.
Used in Pharmaceutical Research:
As a potent acetylcholinesterase inhibitor, [N-methyl-N-phenyl]carbamic acid chloromethyl ester is used in the research and development of drugs targeting the nervous system. Its ability to interfere with the breakdown of acetylcholine can have significant implications for the treatment of various neurological conditions.
Used in Laboratory Settings:
[N-methyl-N-phenyl]carbamic acid chloromethyl ester is also employed in laboratory settings for educational purposes and to conduct experiments related to its chemical properties and potential applications. However, due to its toxicity and potential health hazards, it must be handled with extreme care and under proper safety conditions.

Upstream product

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Relevant academic research and scientific papers

N-substituted carbamoyloxyalkyl-azolium derivatives

N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.

Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole.

A highly potent water soluble triazole antifungal prodrug, RO0098557 (1), has been identified from its parent, the novel antifungal agent RO0094815 (2). The prodrug includes a triazolium salt linked to an aminocarboxyl moiety, which undergoes enzymatic activation followed by spontaneous chemical degradation to release 2. Prodrug 1 showed high chemical stability and water solubility and exhibited strong antifungal activity against systemic candidiasis and aspergillosis as well as pulmonary aspergillosis in rats.

α-Haloalkyl Haloformates and Related Compounds 3.1 A Facile Synthesis of Symmetrical and Unsymmetrical Ureas via Chloromethyl Carbamates

Chloromethyl carbamates were prepared by the reaction of chloromethyl chloroformates with amines and found to produce mono-, symmetrically or unsymmetrically di- and trisubstituted ureas including their N-hydroxy and N-alkoxy derivatives in moderate to good yield.