18636-41-4Relevant academic research and scientific papers
New thalidomide-resembling dicarboximides target ABC50 protein and show antileukemic and immunomodulatory activities
Cie?lak, Marcin,Ka?mierczak-Barańska, Julia,Królewska-Golińska, Karolina,Napiórkowska, Mariola,Stukan, Iga,Wojda, Urszula,Nawrot, Barbara
, (2019/10/28)
We identified novel dicarboximides that were selectively cytotoxic towards human leukemia cells. Using chemical and biological methods, we characterized the biological activity, identified cellular protein targets and defined the mechanism of action of th
