186370-76-3Relevant academic research and scientific papers
Peptide inhibitors of dengue virus NS3 protease. Part 1: Warhead
Yin, Zheng,Patel, Sejal J.,Wang, Wei-Ling,Wang, Gang,Chan, Wai-Ling,Rao, K.R. Ranga,Alam, Jenefer,Jeyaraj, Duraiswamy A.,Ngew, Xinyi,Patel, Viral,Beer, David,Lim, Siew Pheng,Vasudevan, Subhash G.,Keller, Thomas H.
, p. 36 - 39 (2007/10/03)
Substrate-based tetrapeptide inhibitors with various warheads were designed, synthesized, and evaluated against the Dengue virus NS3 protease. Effective inhibition was achieved by peptide inhibitors with electrophilic warheads such as aldehyde, trifluorom
