186376-88-5Relevant academic research and scientific papers
Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors
Ksander, Gary M.,De Jesus, Reynalda,Yuan, Andrew,Ghai, Raj D.,McMartin, Colin,Bohacek, Regine
, p. 506 - 514 (2007/10/03)
The design, synthesis, and biochemical profile of meta-substituted benzofused macrocyclic lactams are described. The meta-substituted benzofused macrocyclic lactams were designed to have a degree of flexibility allowing the amide bond to occupy two comple
