186407-95-4Relevant academic research and scientific papers
AlCl3and BDMAEE: A pair of potent reactive regulators of aryl grignard reagents and highly catalytic asymmetric arylation of aldehydes
Fan, Xin-Yuan,Yang, Yong-Xin,Zhuo, Fang-Fang,Yu, Sheng-Li,Li, Xiao,Guo, Qi-Peng,Du, Zhi-Xue,Da, Chao-Shan
, p. 7988 - 7991 (2010)
Figure Presented Cheap, energy-saving, and applicable: With the aid of AlCl3 and BDMAEE [2,2′-oxybis(N,N-dimethylethanamine)], a highly asymmetric catalytic addition of various aryl Grignard reagents to aldehydes was achieved under mild conditions with easily prepared (S)-H 8-BINOL and inexpensive commercially available Ti(OiPr)4 (see scheme), and the reaction could be easily scaled up with no loss of yield and enantioselectivity.
