186424-34-0Relevant academic research and scientific papers
Synthesis and reactions of reduced flavones
Groundwater, Paul W.,Hibbs, David E.,Hursthouse, Michael B.,Nyerges, Miklos
, p. 163 - 169 (2007/10/03)
The cycloadditions of a series of 4H-pyran-4-ones 3c-e with electron-rich dienes 11a,b to give reduced flavones 12 is described. The subsequent reactions of these reduced flavones with HCl, trifluoroacetic anhydride, ethyl anthranilate 19a and anthranilon
An efficient synthesis of reduced flavones via Diels-Alder addition to 4H-pyran-4-ones
Groundwater, Paul W.,Hibbs, David E.,Hursthouse, Michael B.,Nyerges, Miklo?s
, p. 745 - 749 (2007/10/03)
The 4H-pyran-4-one (4c) undergoes Diels-Alder cycloaddition with electron-rich dienes to give the reduced flavones (7)., whereas the pyran-4-one (4b) and 2-phenyl-4H-pyran-4-one (4a) are unreactive. The 3D structure of the adduct 7a of 4c with Danishefsky's diene (6a) was confirmed by X-ray crystallography.
