186448-78-2

Upstream product

• 186448-77-1 (R)-2-Benzenesulfonyl-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-[1,3]dithian-2-yl-butan-1-ol 
• 157837-33-7 tert-Butyl-((R)-2-[1,3]dithian-2-yl-propoxy)-diphenyl-silane 
• 186448-73-7 Toluene-4-sulfonic acid (R)-2-[1,3]dithian-2-yl-propyl ester 
• 157837-34-8 2-((R)-2-Benzenesulfonyl-1-methyl-ethyl)-[1,3]dithiane 
• 186448-74-8 2-((S)-2-Iodo-1-methyl-ethyl)-[1,3]dithiane 
• 131233-29-9 (R)-2-(1,3-dithian-2-yl)-1-propanol 
• 873-55-2 sodium benzenesulfonate 

Downstream Products

• 186448-91-9 (E)-(1S,2R,5R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-{2-[(1R,3S)-4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-butyl]-[1,3]dithian-2-yl}-5-[1,3]dithian-2-yl-3-methyl-hex-3-en-1-ol 
• 164592-63-6 C₅₈H₁₀₆O₈S₄Si₂ 
• 186449-18-3 C₅₇H₁₀₀Br₂O₅S₄Si₂ 
• 186449-00-3 (E)-(1S,2R,5R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-{2-[(1R,3S)-4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-butyl]-[1,3]dithian-2-yl}-5-[1,3]dithian-2-yl-3-methyl-hex-3-en-1-ol 
• 186448-81-7 Toluene-4-sulfonic acid (E)-(2R,5R)-2-hydroxy-5-{2-[(2S,3R)-2-(4-methoxy-benzyloxy)-4-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-3-methyl-butyl]-[1,3]dithian-2-yl}-3-methyl-hex-3-enyl ester 
• 186449-04-7 2-[(E)-(1S,2R,5R)-2-(tert-Butyl-dimethyl-silanyloxy)-5-[1,3]dithian-2-yl-1-methoxy-3-methyl-hex-3-enyl]-2-[(1R,3S)-4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-butyl]-[1,3]dithiane 
• 186448-83-9 2-[(E)-(1R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-iodo-1,3-dimethyl-pent-2-enyl]-2-[(2S,3R)-2-(4-methoxy-benzyloxy)-4-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-3-methyl-butyl]-[1,3]dithiane 
• 186448-82-8 (E)-(2R,5R)-1-Iodo-5-{2-[(2S,3R)-2-(4-methoxy-benzyloxy)-4-((1S,3R,4R)-3-methoxy-4-triisopropylsilanyloxy-cyclohexyl)-3-methyl-butyl]-[1,3]dithian-2-yl}-3-methyl-hex-3-en-2-ol 
• 186448-86-2 Triisopropyl-((1R,2R,4S)-2-methoxy-4-{(2R,3S)-3-(4-methoxy-benzyloxy)-2-methyl-4-[2-((E)-(R)-1-methyl-3-(R)-oxiranyl-but-2-enyl)-[1,3]dithian-2-yl]-butyl}-cyclohexyloxy)-silane 
• 186448-94-2 2,2-Dimethyl-propionic acid (E)-(2R,5R)-2-(tert-butyl-diphenyl-silanyloxy)-5-[1,3]dithian-2-yl-3-methyl-hex-3-enyl ester 
• 186448-96-4 (E)-(2R,5R)-2-(tert-Butyl-diphenyl-silanyloxy)-5-[1,3]dithian-2-yl-3-methyl-hex-3-en-1-ol 
• 186448-98-6 (E)-(2R,5R)-2-(tert-Butyl-diphenyl-silanyloxy)-5-[1,3]dithian-2-yl-3-methyl-hex-3-enal 
• 186449-08-1 C₅₉H₁₀₈O₈S₄Si₂ 
• 164592-79-4 C₅₇H₁₀₂O₇S₄Si₂ 

Relevant academic research and scientific papers

Rapamycin synthetic studies. 1. Construction of the C(27)-C(42) subunit

A convergent synthetic approach to the C(27)-C(42) fragment of the immunosuppressive macrocycle rapamycin is described.