186495-93-2 Usage
Uses
Used in Pharmaceutical Research and Development:
(-)-4,4-Bis(3-fluorophenyl)butan-2(S)-amine hydrochloride is used as a chemical intermediate for the synthesis of chiral molecules and drug discovery. Its unique stereochemistry and properties make it a valuable compound in the development of new pharmaceuticals and therapeutic agents.
Used in Synthesis of Chiral Molecules:
In the field of organic chemistry, (-)-4,4-Bis(3-fluorophenyl)butan-2(S)-amine hydrochloride is used as a building block for the synthesis of chiral molecules. Chiral molecules have non-superimposable mirror images and are essential in various applications, including pharmaceuticals, agrochemicals, and materials science.
Used in Drug Discovery:
(-)-4,4-Bis(3-fluorophenyl)butan-2(S)-amine hydrochloride may also be utilized in drug discovery processes. Its unique structure and properties can contribute to the development of new drugs with improved efficacy, selectivity, and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 186495-93-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,4,9 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 186495-93:
(8*1)+(7*8)+(6*6)+(5*4)+(4*9)+(3*5)+(2*9)+(1*3)=192
192 % 10 = 2
So 186495-93-2 is a valid CAS Registry Number.
186495-93-2Relevant academic research and scientific papers
Moe, Scott T.,Smith, Daryl L.,DelMar, Eric G.,Shimizu, Scot M.,Van Wagenen, Bradford C.,Balandrin, Manuel F.,Chien, Yongwei,Raszkiewicz, Joanna L.,Artman, Linda D.,White,Mueller, Alan L.
, p. 2411 - 2415 (2000)
The stereoselective synthesis and biological activity of NPS 1407 (4a), (S)-(-)-3-amino-1,1-bis(3-fluorophenyl)butane, a potent, stereoselective antagonist of the NMDA receptor, are described. The racemate (4) was found to be active at the NMDA receptor in an in vitro assay, prompting the synthesis of the individual stereoisomers. The S isomer (4a) was found to be 12 times more potent than the R isomer (4b). Compound 4a demonstrated in vivo pharmacological activity in neuroprotection and anti-convulsant assays. (C) 2000 Elsevier Science Ltd.
