18651-39-3

Upstream product

• 18651-40-6 5,7-dimethoxy-2,3-diphenyl-chromen-4-one 
• 39604-66-5 2-hydroxy-4,6-dimethoxyphenyl benzyl ketone 
• 727-71-9 2-phenyl-2',4',6'-trihydroxyacetophenone 
• 93-97-0 benzoic acid anhydride 

Downstream Products

• 18655-43-1 5-hydroxy-7-methoxy-2,3-diphenyl-chromen-4-one 
• 111301-28-1 2,3-diphenyl-5-hydroxy-8H-4-oxobenzo-<1,2-b:5,6-b'>dipyran 
• 111301-33-8 Acetic acid 4-oxo-2,3-diphenyl-4H,8H-pyrano[2,3-f]chromen-5-yl ester 
• 87288-51-5 Acetic acid 2,2-dimethyl-6-oxo-7,8-diphenyl-2H,6H-pyrano[3,2-g]chromen-5-yl ester 
• 344599-55-9 5-Hydroxy-8,8-dimethyl-2,3-diphenyl-8H-pyrano<2,3-h>chromone 
• 87288-50-4 5-Hydroxy-8,8-dimethyl-2,3-diphenyl-8H-pyrano<3,2-g>chromone 
• 165558-03-2 7-(3-Chloro-propoxy)-5-hydroxy-2,3-diphenyl-chromen-4-one 
• 111301-27-0 7-propargyloxy-5-hydroxy-3-phenylflavone 
• 87288-49-1 5-Hydroxy-2,3-diphenyl-7-(1,1-dimethylpropargyloxy)chromone 

Relevant academic research and scientific papers

COMPOUNDS FOR IMMUNOPOTENTIATION

Methods of stimulating an immune response and treating patients responsive thereto with 3,4-di(1H-indol-3-yl)-1H-pyrrole-2,5-diones, staurosporine analogs, derivatized pyridazines, chromen-4-ones, indolinones, quinazolines, nucleoside analogs, and other small molecules are disclosed.

A Study of the Base-catalysed Wessely-Moser Rearrangement of Angularly Condensed 2,2-Dimethyl-2H-pyrano Derivatives of 5-Hydroxy-2-methylchromones and 2,3-Diphenylchromones and related 1-Hydroxyxanthone

2-Methyl group in 5-hydroxy-2,8,8-trimethyl-8H-pyranochromone (4a) does not hinder base-catalysed isomerisation to afford the corresponding linear isomer (5a); whereas the presence of of phenyl group in position 2 and 3 as in 4c brings no such change.Similarly, 6-hydroxy-3,3-dimethyl-3H-pyranoxanthone (8) does not undergo alkali isomerisation. 5,7-Dihydroxy-2-methylchromone (2a) with 2-chloro-2-methyl-3-butyne in the presence of K2CO3, KI and DMF yields both the linear and angular 2,2-dimethyl-2H-pyrano derivatives (5a and 4a respectively) besides the 1,1-dimethylpropargyl ether (3a), the ratio being 2:4:3.However, under similar conditions 5,7-dihydroxy-2,3-diphenylchromone (2b) yields 3b, 4c and 5c in the ratio of only 5:14:1; again the tendency of forming linear isomer (5c) is far less than that of the angular isomer (4c).