186521-04-0 Usage
Functional groups
Bromine atom, two ether functional groups
Structure
Benzene ring with a bromine atom at the 1st position and an ethoxymethoxy group at the 2nd position
Reactivity
Known for its reactivity in various chemical reactions
Applications
Used in organic synthesis, pharmaceutical research, drug development, and as a building block for the preparation of other organic compounds
Potential uses
Synthesis of pharmaceuticals and fine chemicals due to its versatile reactivity and functional groups
Industry relevance
Valuable chemical intermediate with potential uses in various industries
Check Digit Verification of cas no
The CAS Registry Mumber 186521-04-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,5,2 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 186521-04:
(8*1)+(7*8)+(6*6)+(5*5)+(4*2)+(3*1)+(2*0)+(1*4)=140
140 % 10 = 0
So 186521-04-0 is a valid CAS Registry Number.
186521-04-0Relevant articles and documents
Synthesis of the Tetracyclic Cores of the Integrastatins, Epicoccolide A and Epicocconigrone A
Jeong, Joo Young,Sperry, Jonathan,Brimble, Margaret A.
, p. 11935 - 11944 (2019)
The integrastatins, epicoccolide A and epicoccongirone A, are natural products containing a unique [6.6.6.6]-tetracyclic core framework that exhibit a broad spectrum of biological activities. A synthesis of the common core of epicoccolide A and epicocconigrone A has been achieved using an umpolung alkylation-lactonization to assemble an isochromanone from which the bridged 1,3-dioxane was readily assembled. A different strategy was required to access the core on the integrastatins; an initial aryllithium addition to an aldehyde, followed by oxidation and treatment of the masked dihydroxyketone with acid gave the desired core structure.
