186522-64-5Relevant academic research and scientific papers
Total synthesis of (+)-azinothricin and (+)-kettapeptin
Hale, Karl J.,Manaviazar, Soraya,George, Jonathan H.,Walters, Marcus A.,Dalby, Stephen M.
supporting information; experimental part, p. 733 - 736 (2009/09/30)
(Chemical Equation Presented) Asymmetric total syntheses of (+)-azinothricin and (+)-kettapeptin have been completed through a common new pathway that exploits a highly chemoselective coupling reaction between the fully elaborated cyclodepsipeptide 5 and the glycal activated esters 3 and 4 at the final stages of both respective syntheses.
Asymmetric synthesis of the C(1)-C(47) backbone of antitumour antibiotic A83586C
Hale, Karl J.,Cai, Jiaqiang,Delisser, Vern M.
, p. 9345 - 9348 (2007/10/03)
Protected pentapeptide 9 has been converted to hexapeptide 3 and this chemoselectively coupled to activated ester 2 to give 1 after glycal hydration during SiO2 flash chromatography.
