186586-76-5

Basic information

• Product Name: rel-(1S,4R)-2-phenyl-2-azabicyclo[2.2.1]hept-5-en-3-one
• Synonyms: rel-(1S,4R)-2-phenyl-2-azabicyclo[2.2.1]hept-5-en-3-one
• CAS NO: 186586-76-5
• Molecular Weight: 185.225
• Mol File: 186586-76-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: rel-(1S,4R)-2-phenyl-2-azabicyclo[2.2.1]hept-5-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: rel-(1S,4R)-2-phenyl-2-azabicyclo[2.2.1]hept-5-en-3-one(186586-76-5)
• EPA Substance Registry System: rel-(1S,4R)-2-phenyl-2-azabicyclo[2.2.1]hept-5-en-3-one(186586-76-5)

Safety Data

• Hazardous Substances Data: 186586-76-5(Hazardous Substances Data)

Upstream product

• 49805-30-3 2-azabicyclo[2.2.1.]hept-5-en-3-one 
• 98-80-6 phenylboronic acid 
• 603-33-8 triphenylbismuthane 

Relevant articles and documents

Metal-catalyzed reactions between 2-azabicyclo[2.2.1]hept-5-en-3-ones and arylboronic acids

Cu- and Rh-catalyzed coupling reactions of 2-azabicyclo[2.2.1]hept-5-en-3- ones (1) with arylboronic acids were successful carried out under microwave irradiation conditions and yielded N-aryl and C-aryl derivatives of 1, respectively.

Promotion of reaction of N-H bonds with triarylbismuth and cupric acetate

Arylation of a diverse group of N-H containing compounds at room temperature with triarylbismuth and cupric acetate in the presence of a tertiary amine promoter, such as triethylamine or pyridine, is described. This mild and highly efficient procedure, which is based on Barton's earlier work on the arylation of amines, can be applied to amides, imides, ureas, carbamates, and sulfonamides. Copyright (C) 1996 Elsevier Science Ltd.