186641-06-5Relevant academic research and scientific papers
Synthesis of enantiomerically pure amino acids containing 2,5- disubstituted THF rings in the molecular backbone
Schrey, Anna,Osterkamp, Frank,Straudi, Alrun,Rickert, Corry,Wagner, Holger,Koert, Ulrich,Herrschaft, Bernhard,Harms, Klaus
, p. 2977 - 2990 (2007/10/03)
N- and C-protected derivatives of 2,5-disubstituted trans-and cis-THF amino acids 6 and 7 were prepared in enantiomerically pure form from L- alanine. Felkin-Anh-controlled reduction of the ketone 9 was achieved with a 85:15 diastereoselectivity. Epoxidat
