186689-02-1

Basic information

• Product Name: (S)-3-(4-benzyloxy-3-hydroxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid
• Synonyms: (S)-3-(4-benzyloxy-3-hydroxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid
• CAS NO: 186689-02-1
• Molecular Weight: 387.433
• Mol File: 186689-02-1.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-(4-benzyloxy-3-hydroxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(4-benzyloxy-3-hydroxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid(186689-02-1)
• EPA Substance Registry System: (S)-3-(4-benzyloxy-3-hydroxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid(186689-02-1)

Safety Data

• Hazardous Substances Data: 186689-02-1(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 60-18-4 L-tyrosine 
• 3978-80-1 Boc-Tyr-OH 
• 186689-03-2 2-(tert-butoxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propanoic acid 
• 1025842-35-6 (S)-3-(4-Benzyloxy-3-formyloxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid 

Downstream Products

• 83118-65-4 Isodityrosine 
• 193410-66-1 methyl N-[(1,1-dimethylethoxy)carbonyl]-O-[S]-[5-({[2-(1,1-dimethylethoxy)carbonyl]amino}-2-[(phenylmethoxy)carbonyl]ethyl)-2-(phenylmethoxy)phenyl]-L-tyrosinate 
• 1096164-98-5 [(S)-2-(4-benzyloxy-3-hydroxy-phenyl)-1-methylcarbamoyl-ethyl]-carbamic acid tert-butyl ester 
• 1096165-00-2 2-[(S)-3-(4-benzyloxy-3-hydroxy-phenyl)-2-tert-butoxycarbonylamino-propionylamino]-2-methyl-propionic acid methyl ester 
• 1096165-12-6 C₂₁H₂₆N₂O₅ 
• 586954-09-8 4-hydroxy-3-[2H₃]-methoxyphenylalanine 
• 224824-21-9 N-(tert-butyloxycarbonyl)-3-(3-hydroxy-4-benzyloxyphenyl)-L-alanine benzyl ester 

Relevant articles and documents

Synthesis of new DOPA derivative from l-tyrosine for construction of bioactive compound

A practical synthetic method of new DOPA derivative was developed with L-tyrosine as starting material. The new DOPA analogue could be used in building bioactive compounds.

AMINO ACID DERIVATIVES

Compounds of formula (I) or formula (11) have dopaminergic activity: wherein: R1 is a carboxyl, carboxyl ester, or carboxamide group; R2 is a group - C(=O)-NR3R4, or -S(=O)2-NR3R4; R3 and R4 are independently selected from hydrogen,optionally substituted C1-C6 alkyl, (C1-C5 fluoroalky1)-CH2-, -Q, and -CH2Q, wherein Q is an optionally substituted monocyclic carbocyclic or heterocyclic ring of (3) to (6) ring atoms; or R3 and R4 together with the nitrogen to which they are attached form an optionally substituted monocyclic cycloalkyl or non-aromatic heterocyclic ring of (3) to (8) ring atoms; R5 is hydrogen, or a natural or non-natural alpha amino acid residue linked via a peptide bond; R6 is hydrogen or a group R7C(=O)-; and R7 is C1- C6 alkyl, C1-C6 fluoroalkyl or cyclopropyl