186689-75-8Relevant academic research and scientific papers
Synthesis and biochemical/pharmacological profile of the novel leukotriene B4 receptor antagonist sodium (1S*,3S*)-1-hydroxy-3-[(3 R*S*, E)-3-hydroxy-7-phenyl-1-hepten-1-yl]-1-cyclohexane acetate
Hullot, Pierre,Poudrel, Jean-Marc,Muller, Agnes,Escale, Roger,Rossi, Jean-Claude,Girard, Jean-Pierre,Bonne, Claude
, p. 51 - 58 (2007/10/03)
A novel series of leukotriene B4 (LTB4) antagonists is reported. These compounds present a cyclohexane ring in their chemical structure, which mimics the three conjugated double bonds of LTB4. The biochemical/pharmacologic
3-Substituted iodo alkenyl compounds and methods for preparing same
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, (2008/06/13)
Compounds of the formula: SPC1 Where R is hydrogen, methyl or ethyl; R' is hydrogen, a saturated hydrocarbon chain containing from 1 to about 9 carbon atoms, pentene, hexene, cyclohexyl, or benzyl X is hydrogen, pyranoxy, OR" where R" is a hydrocarbon chain containing from 1 to about 5 carbon atoms or benzyl, EQU1 where R"' is a hydrocarbon chain containing from 1 to about 8 carbon atoms or benzyl, or EQU2 where R1 and R2 are each a hydrocarbon chain containing from 1 to about 5 carbon atoms, and n is an integer from 0 to 5 These compounds are key intermediates in the production of prostaglandins and exhibit antibacterial properties.
