186690-22-2

Upstream product

• 68-11-1 mercaptoacetic acid 
• 186690-20-0 (Z)-3-Chloro-3-(4-fluoro-phenyl)-2-(2-methoxy-4-methylsulfanyl-phenyl)-propenal 
• 405-50-5 p-Fluorophenylacetic acid 
• 186690-18-6 (E)-2-(4-Fluoro-phenyl)-3-(2-methoxy-4-methylsulfanyl-phenyl)-acrylic acid 
• 186690-19-7 1-(4-Fluoro-phenyl)-2-(2-methoxy-4-methylsulfanyl-phenyl)-ethanone 
• 15345-40-1 2-methoxy-4-(methylthio)benzaldehyde 

Downstream Products

• 186690-23-3 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-2-methoxy-phenyl)-thiophene 
• 186690-25-5 2-[5-Bromo-2-(4-fluoro-phenyl)-thiophen-3-yl]-5-methanesulfonyl-phenol 
• 186690-24-4 5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-2-methoxy-phenyl)-thiophene 
• 186690-26-6 (2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-{2-[5-bromo-2-(4-fluoro-phenyl)-thiophen-3-yl]-5-methanesulfonyl-phenoxy}-tetrahydro-pyran-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Structure elucidation and synthesis of a metabolite of antiinflammatory drug DUP 697

Structure of the O-glucuronide (2), one of the metabolites of antiinflammatory drug DUP 697 (1), has been elucidated on the basis of spectral data and a total synthesis of it has been accomplished. Since the synthetic route to 2 is an unambiguous one, completion of the synthesis established the assigned structure.