186787-42-8

Basic information

• Product Name: 2-(4-Methanesulfonyl-phenyl)-1-phenyl-2-(4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone
• CAS NO: 186787-42-8
• Molecular Weight: 373.456
• Mol File: 186787-42-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-Methanesulfonyl-phenyl)-1-phenyl-2-(4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methanesulfonyl-phenyl)-1-phenyl-2-(4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone(186787-42-8)
• EPA Substance Registry System: 2-(4-Methanesulfonyl-phenyl)-1-phenyl-2-(4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone(186787-42-8)

Safety Data

• Hazardous Substances Data: 186787-42-8(Hazardous Substances Data)

Upstream product

• 3179-31-5 3-mercapto-1,2,4-triazole 
• 180696-14-4 1-Phenyl-2-bromo-2-(4-(methylsulfonyl)phenyl)ethanone 

Relevant articles and documents

A new series of selective COX-2 inhibitors: 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles

A series of 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles was prepared for evaluation of potency and selectivity against human COX-1 and COX-2 enzymes. This lead to the discovery of L-768,277, a potent and selective COX-2 inhibitor that also demonstrated good in vivo activity.