186792-10-9Relevant articles and documents
Synthesis and Reactions of 1-(2-Oxopropyl)pyridazin-6-ones
Choi, Woo-Yong,Cho, Su-Dong,Kim, Sung-Kyu,Yoon, Yong-Jin
, p. 1307 - 1313 (2007/10/03)
Oxopropylation of 4,5-dihalopyridazin-6-ones with chloroacetone afforded the corresponding 1-(2-oxopropyl) derivatives. Reaction of title compound with nucleophiles such as amines, alkoxides were investigated. In addition, selective reduction of 3-nitro-1-(2-oxopropyl)pyridazin-6-ones with iron/ammonium chloride in two phase solutions or zinc in acetic acid gave the corresponding 3-amino or 3-hydroxyimino derivatives.