186806-40-6Relevant academic research and scientific papers
Enantioselective Synthesis of the C23–C33 Fragment of Aetheramide A and Its C32 Epimer
Peňa?ka, Tibor,Koukal, Petr,Kotora, Martin
, p. 147 - 149 (2018)
The key aetheramide A intermediate with the natural (R,R,R) configuration along with the one having the unnatural (R,S,R) configuration was synthesized. The synthesis of both stereoisomers was accomplished by Suzuki coupling of two advanced chiral building blocks: (R,R)- and (R,S)-vinylboronates and an (R)-iodoalkene. The former was prepared from (R)-mandelic acid, and the latter was prepared by enantioselective allylation of 3-iodoacrylaldehyde.
Phenylglycol metabolites from cultures of the basidiomycete mycena pruinosoviscida BCC 22723
Isaka, Masahiko,Chinthanom, Panida,Sappan, Malipan,Supothina, Sumalee,Boonpratuang, Thitiya
, p. 909 - 914 (2014)
Mycenadiols A-D (1-4, resp.), phenylglycols possessing an ethynyl or vinyl (ethenyl) group were isolated from cultures of the basidiomycete Mycena pruinosoviscida BCC 22723. The structures were elucidated on the basis of NMR-spectroscopic and mass spectrometric data. The absolute configurations of 1 and 2 were determined by synthesis. Compounds 1-4 are synthetically known, but, they have not been previously isolated from natural sources. Copyright
Efficient and diastereoselective synthesis of (+)-goniobutenolide A via palladium-catalyzed ene-yne cross coupling-lactonization cascade
Kotora, Martin,Negishi, Ei-Ichi
, p. 9041 - 9042 (2007/10/03)
(+)-Goniobutenolide A was synthesized in six steps in 21.4% overall yield from (R)-mandelic acid via Pd-catalyzed ene-yne cross coupling-lactonization cascade with essentially complete control of the exocyclic alkene geometry. Copyright (C) 1996 Elsevier Science Ltd.
