18684-88-3

Upstream product

• 156-59-2 cis-1,2-Dichloroethylene 
• 536-74-3 phenylacetylene 

Downstream Products

• 125358-34-1 3,4-bis(4-phenyl-1,3-butadiynyl)-3-cyclobutene-1,2-dione 
• 31552-04-2 (Z)-1-phenyl-3-penten-1-yne 
• 5701-81-5 buta-1,3-diynylbenzene 
• 7608-31-3 Ph₂PC*C-C*CPh 
• 155187-28-3 trimethyl[(3Z)-6-phenylhex-3-ene-1,5-diynyl]silane 
• 702707-15-1 (Z,Z)-1-phenyl-11-(phenylthio)undeca-3,7-diene-1,5,9-triyne 
• 702707-12-8 (Z,Z)-1-phenyl-11-(phenylsulfonyl)undeca-3,7-diene-1,5,9-triyne 
• 1272413-34-9 (Z)-1-(4-methoxyphenyl)-7-phenylhepta-4-en-2,6-diyn-1-ol 
• 1272413-12-3 (Z)-1,7-diphenylhepta-4-en-2,6-diyn-1-ol 
• 1272413-25-8 (Z)-1,7-diphenylhepta-4-en-2,6-diyn-1-one 
• 1272413-39-4 (Z)-1-(4-methoxyphenyl)-7-phenylhepta-4-en-2,6-diyn-1-one 
• 1272413-48-5 2,7-diphenylpyrazolo[1,5-a]pyridine 
• 1272413-57-6 2-(4-methoxyphenyl)-7-phenylpyrazolo[1,5-a]pyridine 
• 152533-56-7 (Z)-pent-3-en-1-yne-1,5-diyldibenzene 

Relevant academic research and scientific papers

Synthesis of 1,5-diphenylpent-3-en-1-yne derivatives utilizing an aqueous B-alkyl Suzuki cross coupling reaction

1,5-Diphenylpent-3-en-1-yne derivatives were isolated in minor quantities from terrestrial plants and exhibited strong anti-inflammatory activity. A cross coupling reaction between B-benzyl-9-BBN and chloroenynes under mild condition was developed resulti

A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines

2,7-Disubstituted pyrazolo[1,5-a]pyridines were synthesized in good chemical yields by the reaction of enediynones with hydrazine, followed by addition of copper chloride. This reaction can tolerate many functional groups.

Substituent effects on the cyclization mode of 7-sulfonyl-3-hepten-1,5- diynes and 11-sulfonylundeca-3,7-dien-1,5,9-triynes

In probing of cycloaromatization of 7-phenylsulfonyl-3-hepten-1,5-diyne systems to generate biradical intermediates under an alkaline condition suggested that the aryl moiety on C3-C4 also plays an important role to switch the Myers cyclization to Schmitt

An iterative approach to cis-oligodiacetylenes

Phenyl-terminated cis-oligodiacetylenes such as 18, containing a π-conjugated backbone with four triple and three double bonds, were synthesized using Pd-catalysed Sonogashira coupling reactions. Compound 18 represents the longest cis-oligoenyne system to date, but it suffers from the drawback of cis/trans isomerization observed in solution. In order to avoid cis/trans isomerization in such cis-oligodicacetylenes, the ene moieties within the oligomeric backbone were locked by incorporation into ring systems. 1,2-Dibromocyclopentene was used as an olefinic building block for this purpose, permitting the iterative synthesis of the cis-oligodiacetylenes 27 and 28, possessing the same π-conjugated backbone as 18. Unlike that compound, however, 27 and 28 are stable both in solution and in the solid state. Whereas X-ray crystallography revealed a completely planar structure for 27 in the single crystal, NMR and computational investigations suggest that a preferred helical conformation is likely in solution.

Polycarbon ligands: Synthesis and characterization of the phosphinodiynes Ph2PC≡C-C≡CR (R = But, Ph, SiMe3),the μ-η1,η2α, β-butadiynyl complexes Ru2(CO)6-(μ-PPh 2

The phosphino-diynes (PPh2C≡C-C≡CR) (R = But, Ph, SiMe3) are obtained in excellent yield from the corresponding diyne anions RC≡C-C≡C- by quenching with PPh2Cl. Monosubstitution on Ru3(CO)