18685-97-7

Usage

Uses

Used in Pharmaceutical Industry:
Paromamine trihydrochloride is used as an intermediate in the synthesis of aminoglycoside antibiotics for its essential role in the production process. These antibiotics are known for their broad-spectrum antimicrobial activity and are commonly used to treat a variety of bacterial infections.
Used in Antibacterial Applications:
Paromamine trihydrochloride contributes to the development of aminoglycoside antibiotics, which are employed as antibacterial agents to combat various bacterial infections. These antibiotics work by inhibiting bacterial protein synthesis, leading to the cessation of bacterial growth and ultimately killing the bacteria.

Upstream product

• 7205-49-4 paromomycin sulfate 

Downstream Products

• 935871-52-6 2'-N-acetyl-paromamine 
• 1407186-55-3 C₄₄H₅₀FN₃O₁₆ 
• 1407186-54-2 C₄₄H₅₁N₃O₁₇ 
• 1407186-53-1 C₅₀H₆₅N₃O₁₇Si 
• 1407186-57-5 C₄₂H₅₇N₃O₁₃Si 
• 23600-10-4 [(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Investigation of RNA-ligand interactions by 19F NMR spectroscopy using fluorinated probes

Spy swap: The interaction between an unlabeled RNA and unlabeled ligands (red hexagon) can be monitored by 19F NMR spectroscopy using small fluorinated diamines (green star) as spy reporters (see scheme). This technique also enables the visualization of the conformational capture of a riboswitch by its ligand. Copyright

Characterization of the enzyme BtrD from Bacillus circulans and revision of its functional assignment in the biosynthesis of butirosin

(Chemical Equation Presented) A functional reassignment: BtrD, a protein encoded in the butirosin gene cluster, functions as a deacetylase rather than a nucleotidyltransferase as previously reported. BtrD was found to selectively catalyze the conversion o