186891-04-3

Basic information

• Product Name: methyl 4-(hydroxy(naphthalen-2-yl)methyl)benzoate
• Synonyms: methyl 4-(hydroxy(naphthalen-2-yl)methyl)benzoate
• CAS NO: 186891-04-3
• Molecular Weight: 292.334
• Mol File: 186891-04-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(hydroxy(naphthalen-2-yl)methyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(hydroxy(naphthalen-2-yl)methyl)benzoate(186891-04-3)
• EPA Substance Registry System: methyl 4-(hydroxy(naphthalen-2-yl)methyl)benzoate(186891-04-3)

Safety Data

• Hazardous Substances Data: 186891-04-3(Hazardous Substances Data)

Upstream product

• 66-99-9 β-naphthaldehyde 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 21473-01-8 2-naphthalenylmagnesium bromide 
• 1571-08-0 methyl 4-formylbenzoate 

Downstream Products

• 186891-19-0 methyl 4-(naphthalen-2-ylmethyl)benzoate 
• 186891-18-9 4-(Naphthalene-2-carbonyl)-benzoic acid methyl ester 
• 70121-90-3 4-(2-naphthylmethyl)benzoic acid 
• 186891-05-4 4-(2-naphthoyl)benzoic acid 
• 174568-24-2 2-(4-Naphthalen-2-ylmethyl-benzoylamino)-benzoic acid methyl ester 
• 174568-32-2 2-[4-(Naphthalene-2-carbonyl)-benzoylamino]-benzoic acid methyl ester 

Relevant articles and documents

Bulky N-Heterocyclic-Carbene-Coordinated Palladium Catalysts for 1,2-Addition of Arylboron Compounds to Carbonyl Compounds

The synthesis of primary, secondary, and tertiary alcohols by the 1,2-addition of arylboronic acids or boronates to carbonyl compounds, including unactivated ketones, using novel bulky yet flexible N-heterocyclic carbene (NHC)-coordinated 2,6-di(pentan-3-yl)aniline (IPent)-based cyclometallated palladium complexes (CYPs) as catalysts is reported. The PhS-IPent-CYP-catalyzed reactions are efficient at low catalyst loadings (0.02–0.3 mol% Pd), and the exceptional catalytic activity for 1,2-addition is attributed to the steric bulk of the NHC ligand. These reactions can yield a wide range of functionalized benzylic alcohols that are difficult to synthesize by classical protocols using highly active organomagnesium or lithium reagents.